Phloretin ameliorates hepatic steatosis through regulation of lipogenesis and Sirt1/AMPK signaling in obese mice
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چکیده
منابع مشابه
Inhibiting glycosphingolipid synthesis ameliorates hepatic steatosis in obese mice.
UNLABELLED Steatosis in the liver is a common feature of obesity and type 2 diabetes and the precursor to the development of nonalcoholic steatohepatitis (NASH), cirrhosis, and liver failure. It has been shown previously that inhibiting glycosphingolipid (GSL) synthesis increases insulin sensitivity and lowers glucose levels in diabetic rodent models. Here we demonstrate that inhibiting GSL syn...
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ژورنال
عنوان ژورنال: Cell & Bioscience
سال: 2020
ISSN: 2045-3701
DOI: 10.1186/s13578-020-00477-1